Most recently, it's been discovered that conolidine and the above mentioned derivatives act over the atypical chemokine receptor three (ACKR3. Expressed in related parts as classical opioid receptors, it binds into a wide arra… Read More


Conolidine blocks ACKR3 from IN enkephalins. This permits more enkephalins to remain in circulation in the human body. For that reason, the body's organic method of combating pain is heightened. This sort of motion helps to mi… Read More